It’s Monday, April 6. In today’s newsletter: What is actually known about hydroxychloroquine, the drug the president is fixated on recommending for COVID-19. Plus: The pandemic seems to be hitting people of color the hardest.
« TODAY IN POLITICS »
Trump’s Miracle Drug
President Trump has tweeted some very questionable information about the coronavirus, most recently hyping “HYDROXYCHLOROQUINE & AZITHROMYCIN,” as a potential treatment for COVID-19. Our staff writer James Hamblin cautions:
While some very early evidence has shown that hydroxychloroquine may influence the course of COVID-19, Trump is overriding his top medical adviser and minimizing serious risks by encouraging Americans to try the drug right now. This brazen dispensation of medical advice from the president is dangerous in ways beyond the potential harm of the drug itself.
What is known about hydroxychloroquine, then?
It is unclear how hydroxychloroquine would work to treat COVID-19, but the drug is one of many now being urgently studied for the treatment of the disease. The drugs being tested include those that could block viral replication, such as remdesivir, and others that may target the way the virus binds to human cells. Still other drugs aim to modulate a person’s immune response, among them a class of drugs known as IL-6 inhibitors. Hydroxychloroquine has the theoretical potential to affect the virus itself or the immune response. In addition to treating malaria, hydroxychloroquine is importantin the treatment of autoimmune diseases such as rheumatoid arthritis and lupus. In those specific conditions, the drug effectively serves to subdue an overactive immune response.
« THE CORONAVIRUS READER »
(Carolyn Kaster / AP)
In this photograph, Joel Albert, of Potomac, Maryland, plays his drums under a canopy of cherry blossoms at the end of March. Our senior editor Alan Taylor has put together this essay of images of warmer days and beautiful flowers returning to the Northern Hemisphere, for all of those who can’t be outside to see them.